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Latest Research

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Model found to determine cause, possible treatment of nerve tumors

U-M Researchers identify cells that cause nervous system disease

Study suggests existing drugs may be useful in treating brain tumors

New nerves grown from fat cells

Innovative Treatments for Neurofibromas

Living proof miracles can happen

Bee product has been shown to suppress growth of NF1 tumors in mice by over 90%

Scientists find new agent to fight genetic disorders -- Zorro-Locked Nucleic Acid

Candidate Schwannomatosis Gene Announced!

Tracing the pathways of neurofibromatosis

-Researchers find genetic flaw starts biochemical domino effect

High-power MRI helps Mayo Clinic surgical team predict outcomes in unusual tumor cases

For kids with high blood pressure, surgery can help when medicines fail

Changes in dietary protein may override inherited skeletal abnormalities

Protein plays broader role than originally thought in neurofibromatosis

Molecular 'brake' found for neurofibromatosis 1

NF1 and a Cholesterol lowering drug / NF Learning Disabilities

UCSF surgeon develops new spinal surgery technique

“Dramatic Advances” Reported At 2005 CTF Consortium in Aspen, CO

Inflammatory cells highly promising target in NF 1

Brain tumor study reveals why treatment efforts fail in Neurofibromatosis

Mouse brain tumors mimic those in human genetic disorder -Neurofibromatosis

Rice University Receives 1.1 Million from the Department of Defense Neurofibromatosis Research

Program to study Neurofibromatosis using an NF fruit fly model that they have developed. This model will help

to identify key Proteins that regulate NF in humans. The hope is that drug companies can use these proteins as

targets for new drugs that will limit or eliminate NF-tumor growth in people.

NF2: First brainstem implants aim to tackle deafness - Two deaf women in

the US have become the first people to undergo the risky procedure of having

implants in their brainstems. The devices are designed to restore hearing by

directly stimulating nerves.

New Clinical Trials / NF Drugs

Pirfenidone in Children and Young Adults with Neurofibromatosis type I and Progressive Plexiform Neurofibromas

Phase 2 Trial of Farnesyltransferase Inhibitor R115777

Researchers identify important function of NF2 tumor suppressor

- Protein plays role in inherited cancer syndrome, may be key to other tumors

Cold Spring Harbor Laboratory 1- The magic behind merlin (NF2)

Cold Spring Harbor Laboratory 2- New discovery about neurofibromin

has promising therapeutic implications for the

treatment of neurofibromatosis type I (NF1)

University of Pennsylvania Medical Center - Newly-discovered

role for Nf1 gene explains heart abnormalities associated with

neurofibromatosis

Philadelphia, PA - Study finds link between common neurological disorder and

Alzheimer's disease

St. Louis, MO - Tiny molecular change inactivates tumor suppressor gene

in neurofibromatosis

Dallas, Texas 1 - Dallas Scientists Find Clues to Rare Disorder Marked by

Tumors on Nerves

Dallas, Texas 2 - Researchers identify cell, genetic environment behind

nerve-tissue tumors that lead to cancer

Los Angeles, CA - NF RESEARCH YIELDS CLUES TO BIOLOGICAL CAUSE

OF LEARNING DISABILITIES AND POSSIBLE TREATMENT

Philadelphia, PA 2 Gene that prevents tumor growth also carries messages from

circadian clock

U of K, Germany Merlin tells when to grow and when to stop ( NF2)